Role of Hypogonadotropic Hypogonadism in Psychosocial Deprivation among Females Patients


  • Shaista Aslam National University of Medical Sciences, Rawalpindi
  • Riffat Iqbal Govt College University, Lahore
  • Rida Fatima Saeed National University of Medical Sciences, Rawalpindi
  • Iqra Yousaf University of Vienna, Austria
  • Rana Khurram Aftab Punjab Institute of Cardiology, Lahore
  • Erum Monis National University of Medical Sciences, Rawalpindi



Delayed sexual maturation, Congenital hypogonadotropic hypogonadism, psychosocial stress, psychological symptoms


Background: Patients with rare diseases such as congenital hypogonadotropic hypogonadism (CHH) are often challenged to be isolated, lack proper medical care and face negative social consequences. Furthermore, pubertal development is the period of rapid and nearly simultaneous transformation of biological, physical, social, and psychological domains of an individual. Hence, the process of personal transformation is also affected in children with pubertal delay. Due to delay in the growth process, the individual looks different from her or his peers and may have negative consequences on the psychological and social interactions. Objective: The disparities in the growth and development may cause an increase in psychosocial problems and negative peer relationship. Hence, this study was designed to observe psychosocial consequences of delayed puberty in female with CHH. Design: Cross sectional study. Place & duration of study: The data were collected from CHH patients visiting public sector hospitals over a period of 18 months. Patients & Methods: The demographic information, complete medical history, psychological and psychosocial symptoms of the 52 female CHH patients were recorded on the questionnaire. Results: The present study demonstrated that most of the patients were frustrated due to poor body image, low self-esteem, feeling themselves behind the peers, and were with complaints of depression and anxiety. The other psychological symptoms include anger, irritability, loneliness, eating and sleeping disturbances. Conclusion: It was concluded that the delayed sexual maturation has resulted in frustration, low self-esteem and increased anxiety and depression in cohort of local females with CHH.




How to Cite

Shaista Aslam, Riffat Iqbal, Rida Fatima Saeed, Iqra Yousaf, Rana Khurram Aftab, & Erum Monis. (2022). Role of Hypogonadotropic Hypogonadism in Psychosocial Deprivation among Females Patients. MedERA - Journal of CMH LMC and IOD, 4(1).

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